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Friday 30 Oct 2015 - 19:09 Makkah mean time-17-1-1437
 Bethesda, U.S. (IINA) - A new study found that an appetite-controlling protein, which plays a role in developing obesity, might be reduced by using a variation of the gene for brain-derived neurotropic factor (BDNF), UPI reported.
Researchers think that boosting a drug in people with the BDNF variation, which is found more often in black and Hispanic people, may help correct obesity-related issues connected to appetite.
The BDNF protein has roles in the brain and nervous levels, and it is responsible for stimulating the feeling of fullness. Researchers were able to analyze brain tissue samples and identify an area of the gene where one single change altered BDNF levels in the hypothalamus, a part of the brain that controls eating and body weight.
"The BDNF gene has previously been linked to obesity, and scientists have been working for several years to understand how changes in this particular gene may predispose people to obesity", said Jack Yanovski, an investigator at the Eunice Kennedy Shriver National Institute of Child Health and Human Development. "This study explains how a single genetic change in BDNF influences obesity and may affect BDNF protein levels. Finding people with specific causes of obesity may allow us to evaluate effective, more-personalized treatments".
"Lower BDNF levels may contribute to obesity", said Joan Han, a researcher at the University of Tennessee Health Science Center. "If these findings are supported by additional studies, boosting BDNF levels may prove beneficial".
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